Podcast: Redefining Nuclear Power with Caroline DeWitte

In this episode of ASME TechCast, Caroline DeWitte explores how advanced reactor technologies are moving from promise to deployment—and what it will take to deliver clean, reliable, and affordable energy at scale. 
 

DeWitte brings a multidisciplinary background to the discussion, combining experience in nuclear engineering, technology commercialization, startups, and energy innovation. She holds a master’s degree in nuclear engineering from MIT and bachelor's degrees in economics and mechanical engineering from the University of Oklahoma. She is currently the co-founder and COO of Oklo, an advanced nuclear company based in Santa Clara, Calif.
 

The conversation examines Oklo’s Aurora powerhouse technology, the role of regulatory progress, and the business models needed to make advanced nuclear energy practical for customers that want clean power without owning or operating a reactor. DeWitte also shares how collaboration, humility, ownership, and pathfinding are helping Oklo turn breakthrough ideas into real-world solutions. 
 

As a Foundational Sponsor of the ASME CATALYZE Summit, Oklo is part of a broader conversation among engineers, industry leaders, innovators, and decision-makers working to accelerate sustainable industrial transformation. Oklo's approach to advanced nuclear power connects to the larger focus of CATALYZE: scaling technologies that support a cleaner, more resilient energy future.